Origin of Paget's cells in Paget's disease

DOI 34 References
  • SHIMIZU Michio
    <i>Department of Pathology, Saitama Medical University, Saitama International Medical Center</i>

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  • Paget病におけるPaget細胞の由来

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Description

The origin of Paget's cells in mammary Paget's disease is considered to be either Toker cells or migration of breast cancer cells to the nipple. On the other hand, extramammary Paget's disease (EMPD) is classified into primary EMPD and secondary EMPD. The origin of Paget's cells in EMPD is considered to be 1) Toker cells (in primary EMPD), 2) migration of underlying cancer cells (rectal cancer, anal cancer etc.) to the epidermis (in secondary EMPD), and 3) migration of cancer cells from the anogenital mammary-like gland to the epidermis.[Skin Cancer (Japan) 2011 ; 26 : 21-27]

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  • Skin Cancer

    Skin Cancer 26 (1), 21-27, 2011

    The Japanese Skin Cancer Society

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