Squamous cell carcinoma presenting histological features of malignant trichilemmoma during development

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  • 当初毛包系悪性腫瘍の組織像を呈した有棘細胞癌の1例

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A 77-year-old woman presented with a four-month history of a red tumor on the left cheek. The lesion had a dome-shaped and stemed tumor, 20×15mm in diameter. Histopathologically, the incisionally biopsied specimen showed the proliferation of clumping cells, basaloid cells and polygonal tumor cells with abundant clear, PAS-positive, diastase-sensitive cytoplasm. There were findings of actinic keratosis on the border of the tumor. No obvious metastatic lesion was found with chest and abdomen CT scan. One month after the biopsy, the nodule grew to 30×25mm in diameter. Surgical specimen showed disappearance of clear cells, prominence of eosinophilic tumor cells, and PAS-negative, and indicated the histopathological feature of well-differentiated SCC. We diagnosed this case as SCC occurred from actinic keratosis and that presented the feature of malignant trichilemmoma in progress. [Skin Cancer (Japan) 2005; 20: 286-290]

Journal

  • Skin Cancer

    Skin Cancer 20 (3), 286-290, 2005

    The Japanese Skin Cancer Society

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