A case of mixed tumor of the skin

DOI 6 References
  • FUJITA Miho
    <i>Department of Dermatology, Hachioji Medical Center of Tokyo Medical University</i>
  • KISHIDA Kousuke
    <i>Department of Dermatology, Hachioji Medical Center of Tokyo Medical University</i>
  • SHIMOKATA Tadasi
    <i>Department of Dermatology, Hachioji Medical Center of Tokyo Medical University</i>
  • MINEMURA Tokuya
    <i>Department of Dermatology, Hachioji Medical Center of Tokyo Medical University</i>
  • NAGATANI Tetsuo
    <i>Department of Dermatology, Hachioji Medical Center of Tokyo Medical University</i>
  • SHIBUYA Makoto
    <i>Department of Pathology, Hachioji Medical Center of Tokyo Medical University</i>
  • SHINTANI Mariko
    <i>Tanaka Dermatology Clinic</i>

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Other Title
  • 皮膚混合腫瘍の1例

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Description

In January 2008, a 68-year-old man visited our department because of a 30-year history of a slowly growing nodule on his neck. Clinical examination revealed a skin-colored, 34×18×7 mm-sized firm nodule on the anterior part of his neck. The clinical diagnosis was pilomatrixoma. The tumor was excised. Histological examination revealed a well-circumscribed lesion located in the dermis. Epithelial components were embedded in a myxoid stroma. The epithelium showed solid cords, epithelial islands, and small non-branching tubules, containing eosinophilic cuticles detected in some areas. Decapitation secretion was not found in the tubules. Neither follicular differentiation nor plasmacytoid cells were found. Epithelial components, solid cords and islands, showed S-100 protein-positive. The inner layer of tubules was stained by anti-pan-keratin antibody, AE1/AE3. Therefore, the patient was diagnosed as having mixed tumor of the skin.[Skin Cancer (Japan) 2009 ; 24 : 53-56]

Journal

  • Skin Cancer

    Skin Cancer 24 (1), 53-56, 2009

    The Japanese Skin Cancer Society

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