Renal renin-angiotensin system —What supports and breaks the circle of life—

Bibliographic Information

Other Title
  • 腎臓レニン・アンジオテンシン系(RAS):生命の環を支え,脅かすもの

Abstract

Since the discovery of renin 100 or more years ago, the renin-angiotensin system (RAS) has been characterized as the circulating system regulating sodium balance and blood pressure, therefore leads to the application for antihypertensive agents. There is increasing evidence that local RAS is situated in many organs, including kidney where it is involved in renal development, renal function and the progression of chronic kidney disease. This article briefly reviews the new development of RAS in renal issues and points the critical role of RAS in life cycle from prenatal to adulthood.

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Details 詳細情報について

  • CRID
    1390001204338500096
  • NII Article ID
    130004495413
  • DOI
    10.3165/jjpn.26.227
  • ISSN
    18813933
    09152245
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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