A case of AIDS-related plasmablastic lymphoma of the upper gingiva

  • Kitamura Naoya
    Department of Oral and Maxillofacial Surgery, Kochi Medical School, Kochi University
  • Mizobuchi Takahiro
    Department of Oral and Maxillofacial Surgery, Kochi Medical School, Kochi University
  • Ohno Seiji
    Department of Oral and Maxillofacial Surgery, Kochi Medical School, Kochi University
  • Yoshizawa Yasumasa
    Department of Oral and Maxillofacial Surgery, Kochi Medical School, Kochi University
  • Yamamoto Tetsuya
    Department of Oral and Maxillofacial Surgery, Kochi Medical School, Kochi University

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Other Title
  • 上顎歯肉に発症したエイズ関連形質芽細胞リンパ腫の1例

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Plasmablastic lymphoma (PBL) is an aggressive non-Hodgkin lymphoma commonly associated with HIV infection. We present here a case of AIDS-related PBL of the maxillary gingiva with a review of the literature. A 61-year-old Japanese man was referred due to gingival swelling around the left maxillary second molar. The lesion was diagnosed as PBL by histological and immunohistochemical analyses of the biopsy specimen. Blood examination revealed that HIV antigen and antibody were positive and HIV-1 quantitative RT-PCR score and CD4 positive cell count were 51,000 copies/ml and 105 cells/μl, respectively. After antiretroviral therapy was started by a hemato-oncologist, the maxillary gingival mass rapidly disappeared without receiving chemotherapy for PBL. Two years after the start of antiretroviral therapy, HIV infection is controlled and there is no recurrence of PBL.

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