骨粗鬆症における FRAX の検討

  • 三宮 将典
    厚生年金高知リハビリテーション病院整形外科
  • 梶谷 充
    厚生年金高知リハビリテーション病院整形外科
  • 安田 舜一
    厚生年金高知リハビリテーション病院整形外科

書誌事項

タイトル別名
  • Examination of the Fracture Risk Assessment Tool (FRAX) in Osteoporosis

この論文をさがす

説明

The world Health Organization (WHO) issued the Fracture Risk Assessment Tool (FRAX) in order to estimate the 10-year fracture probability for patients with osteoporosis. We computed 10-year fracture probabilities using FRAX and compared them with lumbar spine bone mineral density (BMD).<br>This study included 124 patients (13 men and 111 women, aged 50-86 years, mean age 69.8 years). The mean 10-year probabilities for a major osteoporosis-related fracture in individuals aged 50, 60, 70, and 80 years were 5.8%, 10.5%, 19.7%, and 25.1%, respectively. The relationship between the 10-year fracture probability and lumbar spine BMD was negative (r=−0.406). The mean 10-year fracture probabilities for a lumbar spine BMD of under 70%, 70∼79%, and over 80% were 18.4%, 13.9%, and 13.2%, respectively.<br>We considered that the FRAX cut-off value for reduction of osteoporosis-related fractures was 15%. Although FRAX is useful for screening of osteoporosis patients, we think that the 15% cut-off value is not suitable for patients over 80 years of age.

収録刊行物

詳細情報 詳細情報について

問題の指摘

ページトップへ