フラクトオリゴ糖摂取により促進された腸管からのミネラル吸収が骨に及ぼす影響
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- 諸橋 富夫
- 昭和大学歯学部歯科薬理学教室
書誌事項
- タイトル別名
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- The Effect on Bone of Stimulated Intestinal Mineral Absorption Following Fructooligosaccharide Consumption in Rats.
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説明
Several studies have been carried out to establish the role of calcium and magnesium in bone. These minerals may play an important role in bone structure or strength. Fructooligosaccharides (FOS) are known to be stimulators of intestinal mineral absorption. In intact rats, bone volume and the mineral content (Ca, and Mg) of the bone surface are greater in FOS-fed rats. Moreover, a significant relationship exists between the absorption of these minerals and their content in bone. Osteopenia is known to follow total gastrectomy in animals, leading to the severe concordant loss of both cortical and cancellous bone. These findings are similar to senile osteoporosis in humans. Dietary FOS completely prevents the gastrectomy-induced osteopenia in rats. If similar effects are found in humans, an increase in mineral deposition in bone during growth may contribute to the prevention of bone disease with age. Thus FOS might be a promising prebiotic for bone.
収録刊行物
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- 腸内細菌学雑誌
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腸内細菌学雑誌 16 (1), 21-26, 2002
公益財団法人 腸内細菌学会
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詳細情報 詳細情報について
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- CRID
- 1390001204351048576
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- NII論文ID
- 130003717404
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- ISSN
- 13498363
- 13430882
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可