Effect of probiotics on <i>Helicobacter pylori</i> infection

DOI 70 References
  • KAMIYA Shigeru
    Department of Infectious Diseases, Kyorin University School of Medicine

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  • <i>Helicobacter pylori</i>感染症に対するプロバイオティクスの効果

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Abstract

It has been reported that probiotic treatment is useful for Helicobacter pylori infection. In in vitro studies, probiotic bacteria including Lactobacillus, Bifidobacterium, Streptococcus, Clostridium and Saccharomyces inhibited adhesion and growth of H. pylori. In addition, various probiotic bacteria inhibited colonization of H. pylori in gastric mucosa in in vivo studies using germ-free mice, Mongolian gerbils etc. According to many clinical studies including meta-analysis, it has been shown that probiotic treatment decreases the number of H. pylori bacteria increases the eradication rate by inhibiting the proton-pump with antibiotics and prevents various side effects caused by eradication therapy. Use of probiotics, which are very safe for humans, is expected to assist with the eradication of H. pylori infection. <br>

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