Microchip-Based Immunoassay

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  • TACHI Tomoya
    Department of Applied Chemistry, Graduate School of Engineering, Nagoya University
  • KAJI Noritada
    Department of Applied Chemistry, Graduate School of Engineering, Nagoya University MEXT Innovative Research Center for Preventive Medical Engineering, Nagoya University
  • TOKESHI Manabu
    Department of Applied Chemistry, Graduate School of Engineering, Nagoya University MEXT Innovative Research Center for Preventive Medical Engineering, Nagoya University
  • BABA Yoshinobu
    Department of Applied Chemistry, Graduate School of Engineering, Nagoya University MEXT Innovative Research Center for Preventive Medical Engineering, Nagoya University Plasma Nanotechnology Research Center, Nagoya University Health Technology Research Center National Institute of Advanced Industrial Science and Technology (AIST)

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Other Title
  • マイクロチップイムノアッセイ
  • 分析化学総説 マイクロチップイムノアッセイ
  • ブンセキ カガク ソウセツ マイクロチップ イムノアッセイ

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Abstract

Microchip-based immunoassay, which is immunoassay performed on a microchip, has recently been used in various fields owing to its advantages, such as reduction in sample and reagent consumption, short analysis time and simple operation. Different types of immunoassay have been applied to the miniaturization on a microchip. Material and surface modifications of a microchip, introducing and moving samples and detection must be taken into consideration in order to realize a microchip-based immunoassay. Also, the microchip system should be designed according to a type of immunoassay. In the present review article, we explain the types and classifications of immunoassays and describe important points for developing a microchip-based immunoassay. We then introduce several examples of microchip-based immunoassay.<br>

Journal

  • BUNSEKI KAGAKU

    BUNSEKI KAGAKU 56 (7), 521-534, 2007

    The Japan Society for Analytical Chemistry

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