- von Recklinghausen's disease with multiple emphysematous bullae associated with lung cancer; a case report.
A 39-year-old male had café au lait spots of the skin. He had had pneumoplication for multiple emphysematous bullae at 37 years of age. Two years later, chest X-rays revealed a mass shadow originating at the site of the pneumoplication, and fiberscopic lung biopsy showed primary lung carcinoma. Carcinogenesis seems to lead to lung cancer in patients with von Recklinghausen's disease with bullae. Closer follow-up is recommended for patients with von Recklinghausen's disease with emphysematous bullae to find a possible association with lung cancer.
日本呼吸器外科学会雑誌 7 (1), 31-37, 1993