Efficacy of 50% glucose pleurodesis

DOI 15 References
  • Fujino Kousuke
    Department of Thoracic Surgery, National Hospital Organization Minami-Kyushu Hospital
  • Kubota Ichiro
    Department of Thoracic Surgery, National Hospital Organization Minami-Kyushu Hospital
  • Motooka Yamato
    Department of Thoracic Surgery, National Hospital Organization Minami-Kyushu Hospital
  • Ikeda Kouei
    Department of Thoracic Surgery, Faculty of Life Sciences, Kumamoto University
  • Mori Takeshi
    Department of Thoracic Surgery, Faculty of Life Sciences, Kumamoto University
  • Suzuki Makoto
    Department of Thoracic Surgery, Faculty of Life Sciences, Kumamoto University

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  • 50％ブドウ糖液を使用した胸膜癒着術の有効性

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We report that pleurodesis using 50% glucose was successfully performed in patients with pulmonary air leakage after lobectomy and those with pneumothorax who wanted to avoid surgery. We injected 200 ml of 50% glucose and 10 ml of 1% xylocaine into the chest cavity. We treated 11 patients from April to July 2012, and treatment was successful in 9 of them, but unsuccessful in the other 2 cases resulting in changing to pleurodesis with OK-432 to remove the pulmonary air leakage. In the 2 cases, the patients had severe emphysema, and the amounts of pulmonary air leakage were especially large. Although the efficiency of pleurodesis with this method may be weaker in comparison with OK-432, there were few adverse reactions such as chest pain or fever, and it could be safely used in 2 cases with interstitial pneumonia as well. In conclusion, this is easy-to-use, safe, and efficient treatment method and can be applied first as a pleurodesis agent.

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