Clinical experience of intrapleural administration of fibrin glue for secondary pneumothorax with advanced lung cancer

DOI 6 References
  • Nishino Takeshi
    Department of Thoracic, Endocrine Surgery, and Oncology, University of Tokushima Graduate School
  • Takizawa Hiromitsu
    Department of Thoracic, Endocrine Surgery, and Oncology, University of Tokushima Graduate School
  • Yoshida Mitsuteru
    Department of Thoracic, Endocrine Surgery, and Oncology, University of Tokushima Graduate School
  • Kawakami Yukikiyo
    Department of Thoracic, Endocrine Surgery, and Oncology, University of Tokushima Graduate School
  • Sakiyama Shoji
    Department of Thoracic, Endocrine Surgery, and Oncology, University of Tokushima Graduate School
  • Kondo Kazuya
    Department of Thoracic, Endocrine Surgery, and Oncology, University of Tokushima Graduate School

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  • 進行肺癌に合併した続発性気胸に対する胸腔内フィブリン糊注入療法の経験

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Secondary pneumothorax with advanced lung cancer is an intractable and serious pathosis, which directly aggravates patients' Quality of Life (QOL) and prognosis. We first select the intrapleural administration of fibrin glue for secondary pneumothorax with advanvced lung cancer. From April 2009 to May 2012, we encountered 5 patients who developed secondary pneumothorax during treatment for advanced lung cancer. Their average age was 60.8 years old, and 4 of them had squamous cell carcinoma, 1 had adenocarcinoma, and all had unresectable advanced lung cancer. In 4 of them, the point of air leakage could be detected by pleurography, and leakage could be stopped by the intrapleural administration of fibrin glue. All of them could receive chemotherapy or radiotherapy after treatment for secondary pneumothorax. The intrapleural administration of fibrin glue may be an effective and valid treatment for intractable secondary pneumothorax with advanced lung cancer.

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