書誌事項
- タイトル別名
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- Imaging Analysis of Biological Trace Elements
- イメージング ニ ヨル セイタイナイ ビリョウ ゲンソ ノ ブンセキ
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説明
Imaging measurement methods are powerful tools to visualize the distribution and function of trace elements in living systems. A number of trace element imaging studies by radioisotopes and fluorescent probes have contributed to understand their essential roles. Recently, to investigate physiological roles of intrinsic trace elements, many efforts have been made to develop element-selective fluorescent probes such as Ca2+, Mg2+, Cu2+, etc. Zinc is also known to play important roles in biological processes. Although a variety of Zn2+-selective fluorescent probes has been developed, most of them presented so far possess a fluorescent core and a separate part for binding to Zn2+ within the molecule, so that the molecular weight is usually large and the molecules are hydrophobic. As a result, the applications of such molecules often face difficulties due to their low solubility in aqueous media. Thus, we developed lowmolecular-weight Zn2+ fluorescent probes based on a bipyridine scaffold to detect the Zn2+ levels in cellular systems.
収録刊行物
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- Biomedical Research on Trace Elements
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Biomedical Research on Trace Elements 23 (4), 221-229, 2012
日本微量元素学会
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詳細情報 詳細情報について
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- CRID
- 1390001204366118528
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- NII論文ID
- 10031147239
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- NII書誌ID
- AN10423256
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- COI
- 1:CAS:528:DC%2BC3sXovFOqsbY%3D
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- ISSN
- 18801404
- 0916717X
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- NDL書誌ID
- 024216854
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可