Chemical Synthesis of Furanose Glycosides

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  • Imamura Akihiro
    Department of Applied Bioorganic Chemistry, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu 501-1193, Japan
  • Lowary Todd
    Alberta Ingenuity Centre for Carbohydrate Science and Department of Chemistry, The University of Alberta, Gunning-Lemieux Chemistry Centre, Edmonton, AB T6G 2G2, Canada

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Other Title
  • フラノースグリコシドの化学合成
  • フラノースグリコシドの化学合成[含 英語文]
  • フラノースグリコシド ノ カガク ゴウセイ ガン エイゴブン

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Abstract

Many bacterial, fungal, parasitical and plant species produce glycans containing O-furanoside linkages. These glycoconjugates are often essential for the viability of the organisms that produce them, and an increasing amount of work focused on their chemical synthesis has been carried out in recent years. However, despite these advances, compared to the synthesis of pyranose glycosides, this area has been poorly investigated. In this review we highlight the challenges inherent in the synthesis of furanose glycosides, summarize achievements in the field and suggest directions for future work.

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