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- Izumi Masayuki
- Research Center of Advanced Bionics (RCAB), National Institute of Advanced Industrial Science and Technology (AIST)
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- Uzawa Hirotaka
- Research Center of Advanced Bionics (RCAB), National Institute of Advanced Industrial Science and Technology (AIST)
書誌事項
- タイトル別名
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- Carbohydrate-Based Sensing Materials for Detection of Bacterial Toxins
- サイキン ドクソ ケンシュツ ノ タメ ノ トウサ センシング ザイリョウ ガン エイブン
この論文をさがす
説明
Escherichia coli O157 is an emerging cause of foodborne illness. To avoid the severe complications such as the hemolytic uremic syndrome caused by the infection of the bacterium, rapid diagnosis is very important. In this context, development of a rapid and highly sensitive detection method of Shiga toxins (Stxs), which are produced by the bacterium, is desired. Stxs are a family of AB5 bacterial toxins, which bind to cell surface glycosphingolipid Gb3Cer through multivalent binding of five B-subunits. This paper reviews a recent development of the materials that can bind to the bacterial toxins with high affinities, including artificial glycolipids, molecules containing multivalent binding components, and natural glycolipid layers mimicking the cell membrane.
収録刊行物
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- Trends in Glycoscience and Glycotechnology
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Trends in Glycoscience and Glycotechnology 17 (95), 107-119, 2005
FCCA(Forum: Carbohydrates Coming of Age)
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390001204368725248
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- NII論文ID
- 10016432769
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- NII書誌ID
- AA10995236
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- ISSN
- 18832113
- 09157352
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- NDL書誌ID
- 7401623
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可