重症病態での厚生省DIC scoreのTAT,PIC,血小板数による分析

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  • A Study of DIC based on TAT, PIC and platelets in patients with severe disease.

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Object: DIC is often seen in severe patients in our emergency and critical care center. DIC is often diagnosed using the diagnostic criteria established by the Ministry of Health and Welfare in Japan (1988), and we usually use these criteria. In the present study, we have attempted to develop new criteria for DIC based on TAT, PIC and platelets. Method: TAT, PIC, platelet and DIC scores of 100 patients with various severe diseases seen in the 1989-1991 period, were measured 298 times. We analyzed these data and now propose simple new criteria. Results: Sensitivity and specificity; (1) 0≤PIC≤0.8μg/ml; sensitivity was 95.7%, specificity 98.1%. (2) 0.8<PIC<2.0μg/ml; sensitivity was 82.4%, specificity 85.4%. (3) 2.0μg/ml≤PIC; sensitivity was 85.2%, specificity 98.8%. (4) Total; sensitivity was 89.9%, specificity 93.5%. Conclusion: Simple criteria for DIC, based on TAT, PIC and platelets, are very useful, and we propose the introduction of these simple new criteria for DIC.

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