Development of Conductometric Enzyme Sensors Using Microarray Electrodes

  • MATSUE Tomokazu
    Department of Molecular Chemistry and Engineering, Faculty of Engineering, Tohoku University
  • NISHIZAWA Matsuhiko
    Department of Molecular Chemistry and Engineering, Faculty of Engineering, Tohoku University
  • UCHIDA Isamu
    Department of Molecular Chemistry and Engineering, Faculty of Engineering, Tohoku University

Bibliographic Information

Other Title
  • 微小アレイ電極を用いるコンダクトメトリック酵素素子の開発

Abstract

This paper describes the sensing characteristics of conductive polymer/enzyme-coated microarray electrodes consisting of assembly of microband electrodes with a few μ m width and a few mm length. The sensing principle of the array devices is based on detection of conductometric changes induced by chemical reactions of analytes. The followings are the contents of this paper: 1. Fabrication of ultrathin conductive polymers at hydrophobically-pretreated microarray electrodes. 2. n situ conductivity measurements using microarray electrodes coated with conductive polymers. 3. Redox behavior of polypyrrole-coated microarray electrodes. 4. NADH switching behavior of polypyrrole/diaphorase-coated microarray electrodes. 5. pH sensing behavior of polypyrrole- or polyaniline-coated microarray electrodes. 6. Penicillin sensing behavior of polypyrrole/penicillinase -coated microarray electrodes. 7. Glucose sensing behavior of polyaniline/glucose oxidase-coated microarray electrodes.

Journal

  • NIPPON KAGAKU KAISHI

    NIPPON KAGAKU KAISHI 1995 (7), 493-501, 1995-07-10

    The Chemical Society of Japan

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