Frequency and Characteristic Feature of Metastatic Brain Tumors in Japan

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  • 転移性脳腫瘍の疫学

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The frequency and characteristic features of patients with metastatic brain tumors are summarized in this paper, which was mainly excerpted or re-estimated from the Brain Tumor Registry of Japan. Essence of this paper was as follows, 1)The number of cancer patients who may suffer from metastatic brain tumors was estimated as over 60,000 per year in Japan,calculated by using the data from National Surveillance study in 2000. 2)The recent frequency trend for metastatic brain tumors by primary site are : Increasing : lung cancer, rectal cancer, and renal cancer,Increasing but in small amount : hepatoma,Decreasing : breast cancer, uterus cancer. 3) Metastatic brain tumors with hemorrhagic tendency are : hepatoma, choriocarcinoma, renal cell carcinoma, and melanoma. 4) Frequency of meningeal carcinomatosis from solid cancers by site : Gastric cancer : 35-55%, lung cancer : 25-30%, breast cancer : 10-35%. 5) Cancer patients with metastatic brain tumors died mainly of uncontrolled metastates in other organs in about 70% of all metastatic brain tumors. 6) The prognosis for patients with metastatic brain tumors (2-year survival rates) : Relatively good : head and neck cancer/uterus cancer (40-45%), Fair : renal cell cancer/breast cancer (30%), poor : lung cancer/gastric or colo-intestinal cancer (15-20%)

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