Spontaneous Regression of Meningiomas : A Report of Three Cases

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  • Watanabe Shigeki
    Department of Neurosurgery, Okitama Public General Hospital:Department of Nerusourgery, Yamagata University, Faculty of Medicine
  • Tsuchiya Daisuke
    Department of Neurosurgery, Okitama Public General Hospital
  • Kinjo Toshihiko
    Department of Neurosurgery, Okitama Public General Hospital

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  • 自然縮小した髄膜腫の3例

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We report three rare cases of spontaneous regression of meningiomas. The cases were comprised of three elderly male patients ranging in age from 72 to 79 years old. The tumors were located at the parasagittal region, the middle fossa and the olfactory groove. The tumor volumes were calculated using Cavalieri's Principle: V=4/3×π×a/2×b/2×c/2 (where a, b, and c represent the diameters in three dimensions). These three tumors regressed in size without any intervention and went from 6.1cm^3 to 1.1cm^3 (reduction rate 82%) during 4.5 years in case 1, from 7.2 cm^3 to 3.4 cm^3 (53%) during 6 years in case 2, and from 16.0 cm^3 to 4.0 cm^3 (75%) during 6.5 years in case 3. A closely watched follow-up period is a useful therapeutic option for elderly patients with asymptomatic meningioma.

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