Foreign Body Granulation after Use of Microfibrillar Collagen Hemostat : A Case Report

DOI Web Site 3 Citations Open Access

Bibliographic Information

Other Title
  • Microfibrillar collagen hemostatによる脳内異物性肉芽腫の1例

Search this article

Description

For cases undergoing neurosurgery, Avitene^<[○!R]>, a microfibrillar collagen hemostat (MCH) , a foreign protein extracted from cattle dermis, is routinely used to achieve hemostasis, and this paper presents a case in which foreign body granulation was confirmed to have occurred after MCH use. The patient, a 48-year-old woman, was admitted to hospital because of severe episodic headaches and a right motor weakness. Computerized tomography (CT) revealed a subcortical hemorrhage in the left parietal lobe. Thus the patient underwent a microscopic evacuation of the hematoma, using MCH for the hemostasis. However, 25 days after this operation, the patient developed motor aphasia. CT revealed a ring-enhanced multi-cystic lesion with severe parifocal edema in the cavity of the evacuated hematoma. Magnetic resonance imaging also demonstrated Gd-DTPA enhancement of the wall of this lesion. The patient thus underwent another craniotomy and the lesion was surgically removed. A subsequent histological examination confirmed the formation of foreign body granulation. The clinical significance and differential diagnosis of such a rare pathological entity caused by MCH use are discussed in addition to a review of previously reported cases in the literature.

Journal

Citations (3)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top