Antimicrobial Effects of Silver-zeolite Containing Tissue Conditioners.

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  • Abe Yasuhiko
    Department of Removable Prosthodontics, Hiroshima University School of Dentistry
  • Matsuura Takashi
    Department of Removable Prosthodontics, Hiroshima University School of Dentistry
  • Okamoto Kozo
    Department of Removable Prosthodontics, Hiroshima University School of Dentistry
  • Komura Ikuhiro
    Department of Removable Prosthodontics, Hiroshima University School of Dentistry
  • Sanbuichi Fukunobu
    Department of Removable Prosthodontics, Hiroshima University School of Dentistry
  • Ueshige Morikatsu
    Department of Removable Prosthodontics, Hiroshima University School of Dentistry
  • Akagawa Yasumasa
    Department of Removable Prosthodontics, Hiroshima University School of Dentistry
  • Uchida Masashi
    Zeomic Development Department, Shinagawa Fuel Co., Ltd.

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Other Title
  • 銀ゼオライト含有ティッシュコンディショナーの抗菌効果

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Abstract

The purpose of this in vitro study was to evaluate the antimicrobial effects of tissue conditioners containing an antibiotic ceramic, silver-zeolite (ZM)(Zeomic® AJ 10N, Shinagawa Fuel Co., Nagoya, Japan). Five commercially available tissue conditioners were selected and specimens with ZM (2 wt%) was prepared. Tissue conditioners without ZM and plastic plate were used as a positive control and a negative control respectively. Staphylococcus aureus FDA 209 P, Pseudomonas aeruginosa KM 338 and Candida albicans IFO 1385 were selected as test bacteria. Bacterial suspension (approximately 106 cells) was poured onto the materials (plate-shaped, 10×10×5mm) and they were incubated at 37°C for 0, 24 and 48 hours. Then the number of viable bacteria in the suspension was counted as colony forming unit (CFU). These procedures were also carried out for the materials stored in artificial saliva for 1 week. No CFU of S. aureus, P. aeruginosa and C. albicans was detected on all ZM containing materials. Only S. aureus and C. albicans could form no colony on the positive control materials. Storage in artificial saliva showed no influence on antibiotic effects of these materials. These results indicate that ZM containing tissue conditioners have antimicrobial effects against not only S. aureus and C. albicans but also P. aeruginosa and these effects may persist in saliva.

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