The Double Blind Test on the Effect of Chlorhexidine-Gluconate Containing Mouthwashes on Periodontal Disease

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  • MATSUE Ichiro
    Depertment of Periodontology, Nihon University School of Dentistry at Matsudo
  • SHIMIZU Toru
    Depertment of Periodontology, Nihon University School of Dentistry at Matsudo
  • UMEZAWA Yoshiko
    Depertment of Periodontology, Nihon University School of Dentistry at Matsudo
  • KOTANI Akira
    Department of Dental clinic and oral surgery, Shinshu University Hospital, (Faculty of Medicine)
  • SHIMOJIMA Noriko
    Department of Dental clinic and oral surgery, Shinshu University Hospital, (Faculty of Medicine)
  • SAKAI Fumiko
    Department of Dental clinic and oral surgery, Shinshu University Hospital, (Faculty of Medicine)
  • ASAKUKA Akihito
    Department of oral surgery, Dokkyo University, School of Medicine
  • SAWAMUKA Fumie
    Department of oral surgery, Dokkyo University, School of Medicine
  • KURIHAKA Keiko
    Department of oral surgery, Dokkyo University, School of Medicine
  • TAKASHIMA Michio
    Department of Mathmathics, Faculty of Science and Engineering, Chuo University
  • TAMUIZA Toyoyuki
    Department of Pharmacology, Nihon University, School of Dentistry at Matsudo

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Other Title
  • 歯周疾患に対するマウスウォッシュ (クロルヘキシジン複合口洗液) の二重盲検法による比較検討

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Description

Thirty one patients participated in this study. The effect of Chlorhexidine-Gluconate containing mouthwashes has been evaluated in two groups of thirty one patients during a period of 5 months.<br>In the first group, L-S solution of Chlorhexidine-gluconate and Lactic Alminium and/or in the second group, placebo solution was used five times a day.<br>It is suggested that inhibition of plaque and prevention of gingival inflammation may be controlled by daily mouthrinses of L-S solution of Chlorhexidine-gluconate and Lactic Aluminium compared with placebo solution, provided the agent is administrated in such a way that is reached all teeth surfaces.

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