Incidence of Gingival Hyperplasia in Patients Undergoing Nifedipine Therapy.

  • Yamamoto Eiji
    Department of Periodontology, Asahi University School of Dentistry
  • Takatori Tukasa
    Department of Periodontology, Asahi University School of Dentistry
  • Inuzuka Akihiro
    Department of Periodontology, Asahi University School of Dentistry
  • Kou Yoshitada
    Department of Periodontology, Asahi University School of Dentistry
  • Imai Kenji
    Department of Periodontology, Asahi University School of Dentistry
  • Shiraki Masafumi
    Department of Periodontology, Asahi University School of Dentistry
  • Iwayama Yukio
    Department of Periodontology, Asahi University School of Dentistry
  • Katou Shuji
    Murakami Memorial Hospital, Asahi University School of Dentistry
  • Shinoda Masaaki
    Murakami Memorial Hospital, Asahi University School of Dentistry

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Other Title
  • ニフェジピンの長期服用患者における歯肉増殖の発現頻度調査

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Abstract

We examined the incidence of fibrotic gingival hyperplasia in 42 cardiac patients treated with nifedipine (Adalat ®) during a period of 3 years or more (average: 6.5±2.5y). The mean age of patients (23 males and 19 females) was 65.8±10.0 years. Periodontal examinations were comprised of recording the probing depth, plaque control record, number of remaining teeth and color photograph of gingiva.<BR>Only 2 patients revealed characteristic gingival hyperplasia. The degree of periodontal parameters examined, probing depth, plaque control record and number of remaining teeth, in addition to accumulated dose of drug, were not strongly associated with the appearance of gingival hyperplasia induced by nifedpine.

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