デンチャープラークと咽頭の微生物叢との関連性

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  • Relationship between Denture Plaque and Pharyngeal Microflora.

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Purpose: Prevention of an infection, especially aspiration pneumonia, is an important theme in the elderly. We are pointing out risk that is causing an infection such as the aspiration pneumonia, and a denture acts as a reservoir of microorganisms. The aim of this study was to examine the relationship between denture plaque and pharyngeal microflora in the elderly, and the drug susceptibility of isolated Candida spp.<BR>Methods: We collected samples of denture plaque and pharyngeal plaque from elderly patients in a geriatric hospital and Tokushima University Dental Hospital (TUDH). The microflora was investigated by the detection of oral streptococci, staphylococci, Candida spp., Pseudomonas aeruginosa, Escherichia coli and coliforms, and MRSA. Isolated Candida spp. were measured for drug susceptibility.<BR>Results: The microflora of denture plaque was very similar to pharyngeal microflora. A higher incidence of most microorganisms was observed in the patients in TUDH compared with patients in the geriatric hospital. Staphylococci were detected from the patients who harbored Candida spp. All strains of Candida spp. appeared to be susceptible to amphotericin B. Some strains of C. glabrata, C.tropicalis, and C. krusei appeared to be less susceptible to fluconazole. Fluconazole-resistant C. albicans was not isolated.<BR>Conclusions: Denture plaque strongly influences the pharyngeal microflora in the elderly.

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