A Case of Feline Gastrointestinal Eosinophilic Sclerosing Fibroplasia

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  • Suzuki Manabu
    Small Animal Pathology Service Inc., 86-1 Hanare, Tsukuba, Ibaraki 305-0857, Japan
  • Onchi Miyako
    Sumika Technoservice Corporation, 1-98 Kasugade-naka 3-chome, Konohanaku, Osaka 554-8558, Japan
  • Ozaki Masakazu
    Sumika Technoservice Corporation, 1-98 Kasugade-naka 3-chome, Konohanaku, Osaka 554-8558, Japan

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Feline gastrointestinal eosinophilic sclerosing fibroplasia was diagnosed in an 8-month-old Scottish fold that had a primary gastrointestinal mass involving the stomach, duodenum and mesenteric lymph nodes. Histopathologically, the most characteristic feature of this mass was granulation tissue with eosinophil infiltration and hyperplasia of sclerosing collagen fiber. Immunohistochemically, large spindle-shaped cells were positive for smooth muscle actin and vimentin. This case emphasizes the importance of feline gastrointestinal eosinophilic sclerosing fibroplasia as a differential diagnosis of gastrointestinal neoplastic lesions such as osteosarcoma and mast cell tumor in cats.

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