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- TANAKA Makoto
- Research Promotion Laboratory, Research and Development Center, Otsuka Pharmaceutical Factory, Inc., 115 Kuguhara, Tateiwa, Muya-cho, Naruto, Tokushima 772-8601, Japan
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- SAWAMOTO Osamu
- Research Promotion Laboratory, Research and Development Center, Otsuka Pharmaceutical Factory, Inc., 115 Kuguhara, Tateiwa, Muya-cho, Naruto, Tokushima 772-8601, Japan
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抄録
A spontaneous ameloblastic fibroma was found in a 9-week-old guinea pig. Histopathologically, neoplastic cells consisted of two components: an odontogenic epithelium and odontogenic mesenchyme. The odontogenic epithelium formed strands, nests and islands that were interspersed within the odontogenic mesenchyme. In the marginal region, odontoblasts and scant dysplastic eosinophilic material were seen between these two components. Immunohistochemically, the odontogenic epithelium was positive for cytokeratin AE1/AE3, and the odontogenic mesenchyme and odontoblast were positive for vimentin, in the same manner as in the normal tooth germ (control). We could not obtain conclusive data suggesting that the eosinophilic material was dental hard tissue because the eosinophilic material was not stained specifically by any methods. Based on these histological characteristics, the tumor in the present case was diagnosed as an ameloblastic fibroma. This is the first report of ameloblastic fibroma in guinea pigs.
収録刊行物
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- Journal of Toxicologic Pathology
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Journal of Toxicologic Pathology 26 (3), 325-328, 2013
日本毒性病理学会
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詳細情報 詳細情報について
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- CRID
- 1390001204415938304
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- NII論文ID
- 130003382452
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- NII書誌ID
- AN10232280
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- COI
- 1:STN:280:DC%2BC2c%2FpsV2ltQ%3D%3D
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- ISSN
- 1881915X
- 09149198
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- NDL書誌ID
- 024937356
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- PubMed
- 24155567
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可