Cardiac Rhabdomyoma in a Beagle Dog.

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Cardiac rhabdomyoma was found as an incidental finding in a 6-month-old male beagle dog on microscopic examination. The lesions took a spongy appearance and were located in the subepicardial area of the juncion of the left ventricular wall and the interventricular septum. The cells comprising the lesions had a large vacuole surrounded by a narrow rim of cytoplasm. The cytoplasm of these cells was positive for periodic acid-Schiff’s reaction, but negative after digestion with diastase. Cross-striation was seen in the cytoplasm by phosphotungstic acid hematoxylin staining. No abnormalities were detected by clinical examination, including blood chemistry and electrocardiography. This case might be the first reported cardiac rhabdomyoma in laboratory beagle dogs.

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