脳梗塞における経頭蓋超音波ドプラ（ＴＣＤ）法によるｍｉｃｒｏｅｍｂｏｌｉｃ　ｓｉｇｎａｌｓ（ＭＥＳ）の信号特性

DOI 被引用文献1件 オープンアクセス

書誌事項

タイトル別名
  • Signal Characteristics of Microembolic Signals (MES) by Transcranial Doppler Sonography in Patients with Cerebral Ischemia

この論文をさがす

説明

We investigated the characteristics (velocity and frequency) of microembolic signals (MES) detected by transcranial Doppler (TCD) . The subjects were 22 patients (69 ± 9 years old) with cardioembolic stroke (CE), 28 (65 ± 11 years old) with atherothrombotic stroke (stenosis of the internal carotid or middle cerebral arteries) (AS), 36 (63 ± 10 years old) with lacunar stroke (LS), and 9 (57 ± 16 years old) with mechanical valve replacement (MVR) . Using a Multi-Dop X4 (DWL Co., Germany), a 20-min TCD recording was made over the middle cerebral artery. Signals with an intensity of 6 dB or more above the background Doppler spectrum and associated with harmonic sound were defined as MESS. MESs were detected in 23% of patients with CE (17 signals), 71% (144) of patients with AS, 0% (0) of patients with LS, and 100% (88) of patients with MVR. There was a significant positive correlation (p<0.01) between MES velocity and frequency in all types of disease: AS (r=0.84), CE (r=0.80) and MVR (r=0.91) . The ratio of the velocity of MES (M) to that of background blood flow (B) (MB ratio) in AS (0.65 ± 0.21) was significantly smaller (p<0.05) than that in CE (0.77 ± 0.10) or MVR (0.72 ± 0.14) .<BR>These findings suggest that the frequency of the harmonic sound is related to the velocity of microemboli that traverse the ultrasound beam, and that the velocity of microemboli and duration of MESs are inversely correlated. Most microemboli detected in patients with AS flow close to the vascular walls.

収録刊行物

被引用文献 (1)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ