書誌事項
- タイトル別名
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- The risk factors for severe infantile pertussis: report of 46 infants hospitalized with pertussis
- 重症化危険因子の抽出
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説明
Objectives: To describe clinical features of infantile perussis and investigate the risk factors for severe infantile pertussis.Methods: Retrospective review of medical records of infants hospitalized with a diagnosis of pertussis in our hospital in past 20 years.The risk factors for severe disease (defined as in need of assisted ventilation) were analyzed.Results: 46 infants were enrolled;19 (41%) were <3 months old.None of the subjects had received immunization for pertussis.Complications included seizures in five cases (11%), hypoxia in 18 (39%), apnea in 12 (26%).Nine patients (20%) received assisted ventilation.The factors associated with an increased risk of severe disease were younger infants (<3 months) (odds ratio (OR) 7.3, 95% confidence interval (CI) 1.3 to 40.5), having a comorbidity (OR 8.8, 95%CI 1.3 to 40.5), presenting apnea (OR 22.4, 95%CI 3.6 to 140.0), elevated leukocyte count (>20×109/l) on admission (OR 6.2, 95%CI 1.3 to 30.1), elevated lymphocyte count (>15×109/l) on admission (OR 8.3, 95%CI 1.7 to 41.2), higher maximum C-reactive protein (>1.0 mg/dl) (OR 14.0, 95%CI 2.0 to 97.3).Conclusions: Severe disease is frequent in infantile pertussis.These risk factors should be evaluated early in the course, and those who have a risk factor should be treated carefully.
収録刊行物
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- 日本小児呼吸器疾患学会雑誌
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日本小児呼吸器疾患学会雑誌 19 (2), 122-129, 2008
日本小児呼吸器疾患学会
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詳細情報 詳細情報について
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- CRID
- 1390001204420920192
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- NII論文ID
- 130001998983
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- ISSN
- 21853754
- 09183876
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可