Validity and Usefulness of Aortic Arch Calcification in Chest X-Ray

DOI Web Site PubMed 被引用文献8件 参考文献73件 オープンアクセス
  • Hashimoto Hiroko
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  • Iijima Katsuya
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  • Hashimoto Masayoshi
    Department of General Medicine, Division of General Medicine Science, Kobe University Hospital, Hyogo, Japan
  • Son Bo-Kyung
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  • Ota Hidetaka
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  • Ogawa Sumito
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  • Eto Masato
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  • Akishita Masahiro
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  • Ouchi Yasuyoshi
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan

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Background: Arterial calcification is associated with cardiovascular (CV) disease, to be leading to vessel wall stiffness and causing the management of hemodynamics in the elderly more difficult. Here, we compared the extent of calcification in the aortic arch by reviewing chest X-rays to that in the abdominal aorta as assessed by more detailed examinations. In addition, the validity of the grading and the relationship of this useful grading to clinical risk factors were evaluated.<BR>Methods and Results: The extent of aortic arch calcification (AAC) on a postero-anterior plain chest X-ray was divided into four grades (0 to 3). First, AAC grade was assessed in patients who underwent two quantitative examinations for abdominal aortic calcification; lateral radiograph of lumbar spine and/or computer tomography, and was positively correlated with the abdominal aortic calcification level. Subsequently, AAC grade in 239 out-patients (115 men; mean age, 61.9 years) was also evaluated, and was 0, 1, 2, and 3 in 46%, 22%, 29%, and 4% of the population, respectively, was significantly associated with pulse pressure and intima-media thickness. AAC grade in patients with diabetes or renal dysfunction was significantly higher than in those without each risk, but there was no association with other risk factors. In addition, AAC grade was positively correlated with risk factor clustering.<BR<>Conclusion: Assessment of AAC detectable on a chest X-ray is very useful and its grade reflects the magnitude of calcified change in the whole aorta. In addition, AAC evaluation may provide supportive information for atherosclerotic risk stratification.

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