Changes in Weight, Cardiovascular Risk Factors and Estimated Risk of Coronary Heart Disease Following Smoking Cessation in Japanese Male Workers: HIPOP-OHP Study
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- Tamura Unai
- Department of Health Sciences, School of Medicine, University of Yamanashi.
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- Tanaka Taichiro
- Department of Health Sciences, School of Medicine, University of Yamanashi.
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- Okamura Tomonori
- Department of Preventive Cardiology, National Cardiovascular Center.
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- Kadowaki Takashi
- Department of Health Science, Shiga University of Medical Science.
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- Yamato Hiroshi
- Department of Health Development, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health.
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- Tanaka Hideo
- Division of Epidemiology and Prevention, Aichi Cancer Center Hospital and Research Institute.
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- Nakamura Masakazu
- Department of Health Promotion and Education, Osaka Medical Center for Health Science and Promotion.
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- Okayama Akira
- The Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association.
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- Ueshima Hirotsugu
- Department of Health Science, Shiga University of Medical Science.
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- Yamagata Zentaro
- Department of Health Sciences, School of Medicine, University of Yamanashi.
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- HIPOP-OHP research group HIPOP-OHP research group
- Investigators and members of the research group are listed in Appendix A
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説明
Aim: It is well established that people gain weight after smoking cessation; however, changes in cardiovascular risk factors and the estimated risk of coronary heart disease following smoking cessation have yet to be fully clarified.<BR>Methods: The participants were 1,995 Japanese male workers at 11 workplaces who participated continuously in the High-risk and Population Strategy for Occupational Health Promotion (HIPOPOHP) study. Participants with a smoking habit had cardiovascular risk factors measured at baseline and over a 4-yr period. Their estimated incidence risk of coronary heart disease was calculated by a formula based on a previous cohort study.<BR>Results: Successful abstainers who had stopped smoking for at least 6 months at the end of the follow-up period had weight gains of approximately 2 kg. These subjects had significant worsening of the following factors compared to continuing smokers: systolic and diastolic blood pressure, total cholesterol, triglyceride and fasting blood sugar levels. In contrast, HDL-cholesterol levels improved significantly. When the overall instantaneous incidence risk of coronary heart disease prior to smoking cessation was assumed to be 1.00, the estimated risk was 0.76 (95%CI: 0.68-0.85) in successful abstainers due mainly to smoking cessation, despite weight gain. <BR>Conclusion: Although smoking cessation leads to weight gain, the estimated risk of coronary heart disease was decreased markedly by smoking cessation.
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ ａｎｄ Ｔｈｒｏｍｂｏｓｉｓ
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Ｊｏｕｒｎａｌ ｏｆ Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ ａｎｄ Ｔｈｒｏｍｂｏｓｉｓ 17 (1), 12-20, 2010
一般社団法人 日本動脈硬化学会
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詳細情報 詳細情報について
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- CRID
- 1390001204432574464
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- NII論文ID
- 130004444367
- 50007671759
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- DOI
- 10.5551/jat.1800
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- COI
- 1:STN:280:DC%2BC3c%2FlvFOrsA%3D%3D
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- ISSN
- 18803873
- 13403478
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- PubMed
- 20081325
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可