Study of the Effects of Space Radiation on Mouse ES cells

DOI Web Site 被引用文献2件 参考文献12件
  • Yoshida Kayo
    Osaka City University, Graduate School of Medicine, Department of Molecular Genetics, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585 Japan.
  • Yoshida Shuhei
    Osaka City University, Graduate School of Medicine, Department of Molecular Genetics, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585 Japan.
  • Eguchi-Kasai Kiyomi
    Radiation Effects Mechanism Research Group, National Institute of Radiological Sciences, 4-9-1, Anagawa, Inage-ku, Chiba 263-8555 Japan.
  • Morita Takashi
    Osaka City University, Graduate School of Medicine, Department of Molecular Genetics, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585 Japan.

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As long-term human space flight is now required for cosmic exploration, the influence of space radiation and microgravity on the human body is an issue of high priority. We plan to launch frozen mouse embryonic stem (ES) cells into space, to expose them to space radiation. After returning to the ground, we will microinject the ES cells into fertilized eggs to produce mice, and evaluate the influence of space radiation on their development and on their descendents.

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