Diagnostic Criteria for Dyslipidemia - Executive Summary of Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases for Japanese

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  • Teramoto Tamio
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Sasaki Jun
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Ueshima Hirotsugu
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Egusa Genshi
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Kinoshita Makoto
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Shimamoto Kazuaki
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Daida Hiroyuki
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Biro Sadatoshi
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Hirobe Kazuhiko
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Funahashi Tohru
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Yokote Kotaro
    Committee for Epidemiology and Clinical Management of Atherosclerosis
  • Yokode Masayuki
    Committee for Epidemiology and Clinical Management of Atherosclerosis

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  • Diagnostic criteria for dyslipidemia — executive summary of Japan Atherosclerosis Society (JAS) guideline for diagnosis and prevention of atherosclerotic cardiovascular diseases for Japanese
  • — Executive Summary of Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases for Japanese

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Epidemiological studies have shown that the incidence of coronary artery disease increases as the LDL- C, TC1-9), and TG10, 11) levels rise and the HDL-C level lowers5, 8, 12) both in Japan and in Western countries (Fig.1). At present, prevalence of coronary artery disease in Japan is much lower than that in Western countries13-16). However, recent increases in the LDL-C and TC levels in Japanese associated with so-called Westernization of diet implies future increases in coronary artery disease. In this guideline, therefore, criteria for the diagnosis of dyslipidemia were defined as in Table 1, with a greater emphasis on the prevention of coronary artery disease.<BR>The first step in this diagnostic procedure is to measure TC, TG, and HDL-C levels after overnight fasting. LDL-C level is then calculated by use of the Friedewald equation (LDL-C=TC – HDL-C – TG/5). The LDL-C level may be measured by a homogenous method especially in the case of postprandial examination or when the TG level is 400 mg/dL or higher.

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