Combined Plasma Exchange and Immunoglobulin Therapy in a Case of Severe Childhood Guillain-Barré Syndorome
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- Taira Yasuaki
- Critical Care Medical Center, Yamaguchi University Hospital
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- Tateishi Akio
- Critical Care Medical Center, Yamaguchi University Hospital
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- Soejima Yoshiyuki
- Critical Care Medical Center, Yamaguchi University Hospital
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- Yamamoto Midori
- Critical Care Medical Center, Yamaguchi University Hospital
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- Kasaoka Shunji
- Critical Care Medical Center, Yamaguchi University Hospital
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- Tanaka Hiroyuki
- Third Department of Internal Medicine, Yamaguchi University Hospital
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- Ichiyama Takashi
- Department of Pediatrics, Yamaguchi University Hospital
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- Fukuda Masamichi
- Department of Pediatrics, Yamaguchi University Hospital
Bibliographic Information
- Other Title
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- 血漿交換および免疫グロブリン大量静注法を施行した小児重症ギランバレー症候群
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Abstract
Plasma exchange (PE) was performed three times within seven days from the onset of symptoms (total exchanged plasma volume; 180ml·kg-1) in a two-year old female child with severe Guillain-Barré syndrome who required mechanical ventilation.<br>This was followed by Immunoglobulin therapy (0.4g·kg-1·day-1) for 5 days. The patieat was weaned from mechanical ventilation on the 34th day in the ICU.<br>Centrifugal PE with a larger circuit volume was complicated by hemodilution, while ultrafiltration PE was complicated by intra-circuit hemolysis. Although the hemodynamics remained stable and no obvious electrolyte abnormalities were observed in this patient, changes in blood constitution should be carefully monitored during PE.<br>Combined immunoglobulin therapy should be considered in cases such as this with aggravated neurological symptoms or decreased plasma constituents such as lipid and globulin after early stage serial PE.
Journal
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- Journal of the Japanese Society of Intensive Care Medicine
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Journal of the Japanese Society of Intensive Care Medicine 3 (1), 47-50, 1996
The Japanese Society of Intensive Care Medicine
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Details 詳細情報について
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- CRID
- 1390001204444322944
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- NII Article ID
- 130003641536
- 10007081183
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- NII Book ID
- AN10474053
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- ISSN
- 1882966X
- 13407988
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed