The investigation of prognosis of hematological malignancies in ICU patients

DOI 1 Citations 5 References
  • Okuda Nao
    Department of Emergency and Critical Care Medicine, Tokushima University Hospital
  • Tsunano Yumiko
    Department of Emergency and Critical Care Medicine, Tokushima University Hospital
  • Kohata Hisakazu
    Department of Emergency and Critical Care Medicine, Tokushima University Hospital
  • Nakataki Emiko
    Department of Emergency and Critical Care Medicine, Tokushima University Hospital
  • Itagaki Taiga
    Department of Emergency and Critical Care Medicine, Tokushima University Hospital
  • Onodera Mutsuo
    Department of Emergency and Critical Care Medicine, Tokushima University Hospital
  • Imanaka Hideaki
    Department of Emergency and Critical Care Medicine, Tokushima University Hospital
  • Nishimura Masaji
    Department of Emergency and Critical Care Medicine, Tokushima University Hospital

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  • 集中治療室に入室した血液悪性腫瘍患者の予後の検討

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Abstract

As knowledge of the pathophysiology of organ dysfunctions has been increasing, so the survival of critically ill patients has been improving. After ICU admission, patients with hematological malignancies, however, are still at high risk. We retrospectively evaluated outcome, and risk factors related to mortality of such patients admitted to our ICU. Reviewing medical records of patients admitted between 2005 and 2011, we collected data for age, gender, reasons for ICU admission, Acute Physiology and Chronic Health Evaluation (APACHE) II score, presence and progress of underlying disease, number of organ dysfunction, pancytopenia, treatment with or without bone marrow transplantation, ventilatory support, including noninvasive positive pressure ventilation (NPPV), cause of death, length of ICU stay, ICU mortality, and hospital mortality. Of the 35 patients we found with hematological malignancies, 20 (57.1%) died in the ICU. ICU mortality was lower in patients with only NPPV than those who were intubated. Number of organ dysfunction was also related to ICU mortality. Patients with hematological malignancies remained poor prognosis. NPPV was thought to be effective to care respiratory failure of those who did not cause severe organ dysfunction.

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