Evaluation of A New Ion Selective Electrode for Ionized Magnesium

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  • イオン選択電極法によるイオン化マグネシウム測定の有用性

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Abstract

The aim of this study was an evaluation of the climical usefulness of a new ion-selective electrode for ionized magnesium (iMg2+). In 36 healthy volunteers (Group-H) and 24 postoperative patients (Group-P), blood levels of iMg2+ were measured by a Stat Profile 8 Analyzer (NOVA Biomedical, U. S. A.).<br>In Group-H, the mean level of whole blood iMg2+ was 0.53±0.04mmol·l-1 and was higher than that of plasma iMg2+ obtained immediately after centrifugation. The mean plasma or serum levels of iMg2+ obtained after centrifugation and preserved at -20°C for one week were lover than those obtained without preservation, respectively. However, when preserved at -80°C, they were not significantly different from those obtained without preservation, respectively.<br>The mean level of whole blood iMg2+ in Group-P (0.43±0.07mmol·l-1) was significantly lower than that in Group-H.<br>We concluded that an ion-selective electrode for iMg2+ was useful for investigation of various pathophysiologic processes related to blood iMg2+ in critically ill patients.

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