Rhabdomyolysis due to water intoxication

DOI 1 Citations 16 References Open Access
  • Kogawa Shoko
    Department of Internal Medicine, Metabolism and Endocrinology, Asahikawa Red Cross Hospital
  • Morikawa Akitsuki
    Department of Internal Medicine, Metabolism and Endocrinology, Asahikawa Red Cross Hospital
  • Hayakawa Mineji
    Division of Emergency and Intensive Care, Hokkaido University Hospital
  • Sawamura Jun
    Division of Emergency and Intensive Care, Hokkaido University Hospital
  • Matsuda Naoyuki
    Division of Emergency and Intensive Care, Hokkaido University Hospital
  • Ishikawa Takehiko
    Division of Emergency and Intensive Care, Hokkaido University Hospital
  • Kameue Takashi
    Division of Emergency and Intensive Care, Hokkaido University Hospital
  • Gando Satoshi
    Division of Emergency and Intensive Care, Hokkaido University Hospital

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Other Title
  • 水中毒によって引き起こされた横紋筋融解症の１症例―急激なナトリウム値補正の関与―
  • 急激なナトリウム値補正の関与

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Description

Rhabdomyolysis is caused by a variety of mechanisms, such as drug intoxication, trauma, electrolytes abnormalites and neuro-muscular disorders. This article describes a 63-year-old male patient developed rhabdomyolysis due to hyponatremia after water intoxination and during its correction. Rhabdomyolysis due to water intoxication is rare, and the mechanism has not yet clearly elucidated. Some investigators suspect that serum electrolytes abnormalities according to sodium-calcium exchanger or changes in serum osmolarity may lead to cell membrane fragility. Our case highlights the clinical importance of serum electrolytes and osmolarity abnormalities as causes of rhabdomyolysis due to water intoxication.

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