書誌事項
- タイトル別名
-
- INTERACTION WITH SNP ALLELE IN MULTIPLE LOCI CONTRIBUTES TO HUMAN SKIN COLOR DIVERSITY
この論文をさがす
説明
Our study aims to clarify molecular basis of human skin color diversity and investigate environmental adaptability to ultraviolet irradiation in order to predict human health risk influenced by severe environments in the future. One hundred and twenty-two Caucasians living in Toledo, Ohio participated in this study. Their back and cheek were measured for melanin value for skin pigmentation index as a quantitative trait. Their buccal cells as samples were collected and used for DNA extraction. DNA was used for SNP genotyping with the technology of Masscode system that involves the two-step PCR amplification and comprises a platform chemistry of cleavable mass spectrometry tags. Our results of statistical analysis show that SNP allele in multiple loci are related and suggest high possibility of linkage disequilibrium. Our study plans to collect data on other ethic groups in order to analyze correlation between SNP allele in multiple loci and identify loci associated with human skin color diversity.
収録刊行物
-
- 日本生理人類学会誌
-
日本生理人類学会誌 12 (1), 1-10, 2007
日本生理人類学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001204455476480
-
- NII論文ID
- 110006242744
-
- NII書誌ID
- AN1052804X
-
- ISSN
- 24320986
- 13423215
-
- 本文言語コード
- ja
-
- 資料種別
- journal article
-
- データソース種別
-
- JaLC
- CiNii Articles
- KAKEN
-
- 抄録ライセンスフラグ
- 使用不可