Gingival Crevicular Fluid Biomarkers in Patients with Gingivitis and Chronic Periodontitis
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- Myriam A. Koss
- Cátedra de Química Biólogica, Facultad de Odontología, Universidad Nacional de Tucumán
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- Cecilia E. Castro
- Cátedra de Química Biólogica, Facultad de Odontología, Universidad Nacional de Tucumán
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- Karina M. Salúm
- Cátedra de Química Biólogica, Facultad de Odontología, Universidad Nacional de Tucumán Cátedra de Periodoncia, Facultad de Odontología, Universidad Nacional de Tucumán
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- Kishimoto Ethuo
- Department of Oral Health, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
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- Takagi Shin
- Department of Oral and Maxillofacial Reconstructive Surgery, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
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- María E. López
- Cátedra de Química Biólogica, Facultad de Odontología, Universidad Nacional de Tucumán
この論文をさがす
説明
To quantify biomarkers of inflammation and tissue destruction in gingivo crevicular fluid to contribute to the diagnosis of the severity of the gingivo—periodontal disease. 115 adults with gingival-periodontal disease were included. Diagnosis was determined through clinical and radiographic criteria. Samples were obtained from six to eight sites per patient. Data were analyzed by an SPSS system using ANOVA One Way and Tukey tests. Volume raised in gingivitis, moderate and severe periodontitis Total proteins and hydroxyproline increased in moderate and severe periodontitis. Electrophoresis evidenced protein bands that increased with the severity of periodontitis. Some were similar to serum proteins and an additional band of less than 14 kDa was present in all the periodontitis samples. Collagenase bands evidenced differences between healthy and diseased subjects. Calcium determinations showed no statistically significant differences among groups. Levels of gingivo crevicular fluid biomarkers specific for inflammation and collagen degradation correlate with the clinical diagnosis in patients with gingivitis and chronic periodontitis.
収録刊行物
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- Journal of Hard Tissue Biology
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Journal of Hard Tissue Biology 19 (2), 111-116, 2010
硬組織再生生物学会
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詳細情報 詳細情報について
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- CRID
- 1390001204457918976
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- NII論文ID
- 130004480499
- 10027421968
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- NII書誌ID
- AA11074332
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- ISSN
- 1880828X
- 13417649
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- NDL書誌ID
- 11005247
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可