Bursting Oscillation in Basal Ganglia Associated with Parkinson's Disease
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- Kubota Shigeru
- Graduate School of Science and Engineering, Yamagata University
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- Rubin Jonathan E.
- Department of Mathematics, Pittsburgh University
Bibliographic Information
- Other Title
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- パーキンソン病における大脳基底核のバースト振動
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Abstract
Symptoms in Parkinson's disease are accompanied by bursting oscillation in the basal ganglia. Although it is clinically important to elucidate the mechanism underlying the oscillatory dynamics, complex interactions among the nuclei in the basal ganglia make it difficult to understand. We review recent hypotheses on the origin of the bursting oscillation, and explain an important role of the subthalamic nucleus and the regions connected to it. We also discuss a computational model on the NMDA-activated burst in the subthalamic nucleus.
Journal
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- The Brain & Neural Networks
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The Brain & Neural Networks 20 (3), 100-107, 2013
Japanese Neural Network Society
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Details 詳細情報について
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- CRID
- 1390001204465971712
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- NII Article ID
- 10031195266
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- NII Book ID
- AA11658570
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- ISSN
- 18830455
- 1340766X
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed
