PREVALENCE OF CHILDHOOD ALLERGIC DISEASES IN JAPAN USING INTERNATIONAL STUDY OF ASTHMA AND ALLEGIES IN CHILDHOOD (ISAAC) PHASE I PROTOCAL

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  • ＩＳＡＡＣ（Ｉｎｔｅｒｎａｔｉｏｎａｌ　Ｓｔｕｄｙ　ｏｆ　Ａｓｔｈｍａ　ａｎｄ　Ａｌｌｅｒｇｉｅｓ　ｉｎ　Ｃｈｉｌｄｈｏｏｄ）　　第Ｉ相試験における小児アレルギー疾患の有症率

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We examined 2, 901 children aged 6-7 years (the primary school children) and 2, 831 children aged 13-14 years (the junior high-school children) in Japan by random sampling method. These children and/or their families reported to have symptoms of three atopic disorders, including asthma, allergic rhinoconjunctivitis, and atopic eczema by ISAAC questionnaires. Furthermore a video asthma questionnaire was performed in the junior high-school children.<br>Results:<br>1. In the primary school children, 17.3% had asthma symptoms, 25.6% had symptoms of allergic rhinoconjunctivitis, and 21.3% had symptoms of atopic eczema. In the junior high-school children, these prevalence were 13.4%, 41.0%, and 13.5%, respectively.<br>2. The investigation using the video questionnaires showed that 10.2% of the junior high-school children experienced wheezing once or more per month and 16.4% had wheezing after exercise.<br>3. In Japan, the prevalence rates of these three disorders were higher than in worldwide, and especially the highest in Asia.<br>4. The wheezy children with more severe symptoms had the higher values of total and house dust mite specific IgE. Further studies are needed to investigate the causes of increasing allergic diseases.

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