A Case of Unilateral Gravid Macromastia in 23-Year-Old Japanese Woman Associated with Elevated Serum CA19-9
-
- Sakai Takehiko
- Division of Breast and Endocrine Surgery, Department of Surgery, Shinshu University School of Medicine
-
- Fujimori Minoru
- Division of Breast and Endocrine Surgery, Department of Surgery, Shinshu University School of Medicine
-
- Tominaga Yoshiaki
- Division of Breast and Endocrine Surgery, Department of Surgery, Shinshu University School of Medicine
-
- Kanai Toshiharu
- Division of Breast and Endocrine Surgery, Department of Surgery, Shinshu University School of Medicine
-
- Ito Ken-ichi
- Division of Breast and Endocrine Surgery, Department of Surgery, Shinshu University School of Medicine
-
- Shingu Kiyoshi
- Division of Breast and Endocrine Surgery, Department of Surgery, Shinshu University School of Medicine
-
- Amano Jun
- Division of Cardiovascular Surgery, Department of Surgery, Shinshu University School of Medicine
-
- Kushima Hideo
- Department of Plastic and Reconstruction Surgery, Shinshu University School of Medicine
-
- Tsuchiya Shin-ichi
- Division of Surgical Pathology, Nihon Medical School Hospital
この論文をさがす
説明
We report a rare case of gravid macromastia (GM) treated after delivery. A 23-year-old woman with left breast enlargement was referred to our hospital. Laboratory investigations revealed an elevated serum CA19-9 level of 200.3 U/ml. Gravid macromastia was diagnosed by clinical examination (US, MRI) and 11G mammotome biopsy. Tumorectomy of the left breast and mammoplasty were performed. The mass had proliferated to the exclusion of normal gland. Histological examination revealed abundant proliferation of stromal loose connective tissue and interposed fat cells surrounding normal and lactating lobules. The epithelial cells were positive for CA19-9 on immunohistochemical staining. Serum CA19-9 decreased to normal levels 3 months after operation. GM is exceedingly rare and occurs in less than 0.001-0.003% of all pregnant women. Once established, the condition is likely to continue to successive pregnancies. This benign tumor is sometimes difficult to distinguish from malignant tumors since it shows few histological characteristics and grows rapidly. Attention is necessary to diagnose tumors of the breast during pregnancy.
収録刊行物
-
- Breast Cancer
-
Breast Cancer 12 (3), 238-242, 2005
日本乳癌学会
