Cancer Chemoprevention by Terpenoids

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  • AKIHISA Toshihiro
    Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University
  • TOKUDA Harukuni
    Department of Biochemistry, Kyoto Prefectural University of Medicine

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Other Title
  • テルペノイドによるがん予防
  • テルペノイド ニ ヨル ガン ヨボウ

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Abstract

Terpenoids occur in all major groups of organisms from fungi to humans as secondary metabolites. Terpenoiods have been revealed to possess anti-tumor promoting activities among various biological activities. In this short review, we discuss the antitumor-promoting activities of mono-, sesqui-, di-, and triterpenes, and sterols, resulting from our own and other research groups' investigation. Terpenoids are minor but ubiquitous components of our diet, and are considered to be relatively non-toxic to humans. These compounds, therefore, constitute possible candidates for cancer chemopreventive agents.

Journal

  • Oleoscience

    Oleoscience 2 (6), 347-354,331, 2002

    Japan Oil Chemists' Society

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