Squamous Cell Carcinoma with Systemic Metastases in a Spotted Seal (<i>Phoca largha</i>)
-
- MICHISHITA Masaki
- Department of Veterinary Pathology, Nippon Veterinary and Life Science University
-
- TORIKAI Kazushi
- Department of Veterinary Pathology, Nippon Veterinary and Life Science University
-
- YOSHIMURA Hisashi
- Department of Veterinary Pathology, Nippon Veterinary and Life Science University
-
- TERASAWA Fumio
- Enoshima Aquarium
-
- NAKAHIRA Rei
- Department of Veterinary Pathology, Nippon Veterinary and Life Science University
-
- OHKUSU-TSUKADA Kozo
- Department of Veterinary Pathology, Nippon Veterinary and Life Science University
-
- TAKAHASHI Kimimasa
- Department of Veterinary Pathology, Nippon Veterinary and Life Science University
Bibliographic Information
- Other Title
-
- ゴマフアザラシ（<i>Phoca largha</i>）の全身転移を伴う扁平上皮癌の一例
- Squamous Cell Carcinoma with Systemic Metastases in a Spotted Seal (Phoca largha)
Search this article
Description
A 31-year-old male spotted seal (Phoca largha) was examined at necropsy. Multiple masses were observed in systemic organs, including the lung, stomach, pancreas, greater omentum, and pulmonary lymph nodes. Histologically, pulmonary masses contained numerous solid nests composed of polygonal tumor cells and often central keratinization, whereas those were less keratinization in the stomach, which tumor emboli were observed in the vessels. On immunohistochemistry, tumor cells were positive for keratin 5, pancytokeratin AE1/AE3, and p63 but negative for vimentin, cytokeratin CAM5.2, and calretinin. Based on macroscopical, histological, and immunohistochemical features, this case was diagnosed as squamous cell carcinoma with systemic metastases. The primary site in this case was probably the lung, with vascular metastases to distant organs including the stomach, omentum, and pulmonary lymph nodes. To the authors' knowledge, this is the first description of squamous cell carcinoma in a spotted seal.
Journal
-
- Japanese Journal of Zoo and Wildlife Medicine
-
Japanese Journal of Zoo and Wildlife Medicine 18 (4), 129-132, 2013
Japanese Society of Zoo and Wildlife Medicine
- Tweet
Details 詳細情報について
-
- CRID
- 1390001204487969024
-
- NII Article ID
- 130003396189
-
- ISSN
- 2185744X
- 13426133
-
- Text Lang
- en
-
- Article Type
- journal article
-
- Data Source
-
- JaLC
- Crossref
- CiNii Articles
- KAKEN
- OpenAIRE
-
- Abstract License Flag
- Disallowed
