Plurihormonal Adenocarcinoma Detected at the Head of a Dalmatian Pelican (<i>Pelecanus crispus</i>)

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  • ハイイロペリカンの頭部に認められた多ホルモン産生腺癌

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Abstract

Adenocarcinoma was found in a Dalmatian pelican (Pelecanus crispus) aged >25 years. A large tumor mass, which was located at the left side of the head, replaced the dura mater, skull and subcutis, and compressed the left hemisphere. In addition, neoplastic lesions were detected in the spleen, lungs and liver. Histologically, the neoplastic cells formed tubular or solid alveolar structures, and appeared to be cytologically malignant. Neoplastic cells reacting to follicle-stimulating hormone, thyroid-stimulating hormone, adrenocorticotrophic hormone, α-melanocyte-stimulating hormone, or growth hormone were demonstrated immunohistochemically. This case is presumably a primary pituitary adenocarcinoma, but the possibility of ectopic pituitary carcinoma can not be absolutely denied.

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