Lung Carcinoma in a Clouded Leopard(<i>Neofelis nebulosa</i>)

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  • ウンピョウ(<i>Neofelis nebulosa</i>)における肺癌の1例

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A rare case of lung carcinoma originating from the left cranial lobe in an over 12-year-old male clouded leopard was studied. Grossly, a large nodule, 85×55×60 mm, in the left cranial lobe, and several small metastatic nodules were observed in the left lung. Dissemination in the left pleura and distinct metastasis in the tracheobronchial lymph nodes and spleen were observed. Microscopically, the pulmonary masses consisted of infiltrative growth of lung carcinoma. The tumor cells were round to cuboidal with high cell atypia and showed irregular glandular patterns. Mitotic figures were common. The tumor cells were positive for keratin and cytokeratin AE 1. Metastasis was observed in the pleura, tracheobronchial lymph nodes, spleen and adrenals. The present case was classified as a bronchiolar-alveolar carcinoma, undifferentiated type.

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