Combined Impact of the Association between Prepregnancy Body Mass Index and Gestational Weight Gain on the Placental/Umbilical Cord Blood Volume Collected

DOI Web Site Web Site 参考文献25件
  • Omori Atsuko
    Department of Radiological Life Sciences, Division of Medical Life Sciences, Hirosaki University Graduate School of Health Sciences
  • Chiba Takako
    Department of Radiological Life Sciences, Division of Medical Life Sciences, Hirosaki University Graduate School of Health Sciences
  • Takahashi Kenji
    Department of Radiological Life Sciences, Division of Medical Life Sciences, Hirosaki University Graduate School of Health Sciences
  • Tanaka Kanako
    Department of Obstetrics and Gynecology, Hirosaki National Hospital
  • Manabe Mami
    Department of Obstetrics and Gynecology, Hirosaki National Hospital
  • Kashiwakura Ikuo
    Department of Radiological Life Sciences, Division of Medical Life Sciences, Hirosaki University Graduate School of Health Sciences

この論文をさがす

抄録

Placental/umbilical cord blood (CB) contains multipotent hematopoietic stem/progenitor cells and has been utilized worldwide both clinically and experimentally. Neonatal birth weight is positively correlated with CB volume and with the total number of nucleated cells associated with engraftment and survival after CB transplantation. Considering the recent increase in the frequency of low birth weight (<2500 g) and the decline in body mass index (BMI) among Japanese women of childbearing age, the present study investigated the combined impact of the prepregnancy BMI and the gestational weight gain on CB volume. From 1998 to 2007, CB samples were obtained from 579 healthy women with singleton vaginal deliveries. The prepregnancy BMI was classified into the underweight, normal, overweight, or obese groups. According to the current gestational weight gain recommendations or other new optimum recommendations, the gestational weight gain was classified into below, within, or above recommendations in each prepregnancy BMI group. The neonatal weight and placental weight had significantly positive effects on the CB volume. Underweight pregnant women demonstrated significantly lower neonatal and placental weight. According to the current recommendations, no significant difference in the CB volume was observed. According to the new optimum recommendations for underweight pregnant women, a significantly higher CB volume was obtained from the group within the recommended weight gain range than from the group below the recommended range. In the underweight group, a higher CB volume could be obtained if the upper limit of the gestational weight gain increases by a few kilograms more than the current gestational weight gain recommendations.

収録刊行物

参考文献 (25)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ