高速原子衝撃イオン化質量分析法(FAB‐MS)の化粧品分析への利用

  • 木村 朋子
    株式会社資生堂研究開発本部安全性・分析センター
  • 吉田 誠一
    株式会社資生堂研究開発本部安全性・分析センター
  • 西谷 宏
    株式会社資生堂研究開発本部安全性・分析センター
  • 高松 翼
    株式会社資生堂研究開発本部安全性・分析センター

書誌事項

タイトル別名
  • Application of Fast Atom Bombardment Ionization-Mass Spectrometry(FAB-MS) to Cosmetic Analysis.

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説明

An optimized FAB-MS measurement method has successfully been incorporated into the systematic analysis method of cosmetic products based upon a stepwise elution silica-gel column chromatography as a skeleton fractionation method and a combined use of 13C-NMR and GC/MS. The system was able to precisely identify the components such as polyoxyalkyleneglycol, oxyalkylated nonionic surfactants, polyglycerin and its derivatives, etc. for their alkyl and/or oxyalkylene chain distributions, which are eluted in the acetone and methanol fractions in silica-gel column chromatography. A simulation was carried out for various cosmetic ingredients based upon the results of spectral analysis and it was constructed in a simple retrieval system using a database of the numerical values and chemical structures. Reflection of a mixture state to the spectrum has been studied semi-quantitatively including an optimization of measuring conditions.

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詳細情報 詳細情報について

  • CRID
    1390001204499706368
  • NII論文ID
    130004188744
  • DOI
    10.5107/sccj.31.66
  • ISSN
    18844146
    03875253
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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