書誌事項
- タイトル別名
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- Optimal Control of Gene Regulatory Networks with External Stimuli
- ガイブ シゲキ オ コウリョ シタ イデンシ ネットワーク ノ サイテキ セイギョ
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説明
In this paper, the optimal control problem of gene regulatory networks modeled by Boolean networks is discussed. In the standard problem formulation, we assume that there exist genes corresponding to control inputs in gene regulatory networks. However, in many systems, this assumption is not satisfied. In this paper, two kinds of control inputs are considered. One is the above control input. The other is the control input corresponding to an external stimulus. An external stimulus does not control the detailed behavior, but can switch Boolean functions probabilistically. So genes corresponding to control inputs may not exist, and this problem formulation is more realistic. Furthermore, the optimal control problem is reduced to an integer linear programming problem.
収録刊行物
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- 計測自動制御学会論文集
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計測自動制御学会論文集 47 (11), 520-526, 2011
公益社団法人 計測自動制御学会
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詳細情報 詳細情報について
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- CRID
- 1390001204504862080
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- NII論文ID
- 10030165490
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- NII書誌ID
- AN00072392
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- ISSN
- 18838189
- 04534654
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- NDL書誌ID
- 023446325
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- 本文言語コード
- en
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