書誌事項
- タイトル別名
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- Adhesion and Internalization of Functionalized Polystyrene Latex Nanoparticles toward the Yeast <i>Saccharomyces cerevisiae</i>
- ポリスチレンラテックスナノ リュウシ ノ コウボ サイボウ エ ノ フチャク ・ トリコミ ゲンショウ ノ ヒョウカ
- Adhesion and Internalization of Functionalized Polystyrene Latex Nanoparticles toward the Yeast Saccharomyces cerevisiae
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抄録
The toxicity and behavior (internalization, adhesion, dispersion) of manufactured polystyrene latex (PSL) nanoparticles (nominal diameter : 50 nm) with various functional groups toward the yeast Saccharomyces cerevisiae as a model eukaryote were examined using the colony count method and microscopic observation. The colony count tests suggested that the PSL nanoparticles with a negative surface charge had little or no toxicity toward the yeast. In contrast, PSL nanoparticles with an amine functional group and a positive surface charge (p-Amine) displayed a high toxicity in 5 mol/m3 NaCl, whereas the p-Amine were mostly unharmed in 154 mol/m3 NaCl, which was quite different with the toxicological effects of Escherichia coli as a model prokaryote. Confocal and atomic force microscopy indicated that in 5 mol/m3 NaCl the p-Amine nanoparticles entirely covered the surface of the yeast, and cell death occurred, whereas in 154 mol/m3 NaCl were internalized by endocytosis, and cell death did not occur.
収録刊行物
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- 粉体工学会誌
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粉体工学会誌 50 (7), 472-477, 2013
一般社団法人 粉体工学会
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詳細情報 詳細情報について
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- CRID
- 1390001204511773568
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- NII論文ID
- 10031185746
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- NII書誌ID
- AN00222757
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- COI
- 1:CAS:528:DC%2BC3sXhtlWrtLvI
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- ISSN
- 18837239
- 03866157
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- NDL書誌ID
- 024761654
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可